GEORGE SUSPECTS AN ANESTHESIOLOGIST OF DRINKING ON THE JOB, AND ALEX TREATS A FORMER SCHOOLMATE WHO MUTILATES HIMSELF, ON ABC'S "GREY'S ANATOMY"

"The Self-Destruct Button" - Derek and Meredith try (unsuccessfully) to be discreet as they spend the night together at Meredith's house, but their haggard appearance speaks volumes to everyone - including Bailey, who warns Meredith to end the relationship. Meanwhile George suspects an anesthesiologist of drinking on the job but is reluctant to speak up about it, Alex treats a former schoolmate who finds honor in self-mutilation, Izzie's boyfriend takes extreme measures in order for them to spend more time together, and Cristina seems to be battling a case of the flu, on "Grey's Anatomy," SUNDAY, MAY 8 (10:02-11:00 p.m., ET) on the ABC Television Network.

"Grey's Anatomy" stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Isaiah Washington as Preston Burke, Katherine Heigl as Isobel "Izzie" Stevens, Justin Chambers as Alex Karev, T.R. Knight as George O'Malley, Chandra Wilson as Miranda Bailey and James Pickens, Jr. as Richard Webber.

Guest starring are Ever Carradine as Athena, Amanda Macdonald as Claire Rice, Kim Morgan Greene as Mrs. Rice and Russell Hornsby as Digby Owens.

"The Self-Destruct Button" was written by Kip Koenig and directed by Darnell Martin.

"Grey's Anatomy" is broadcast in 720 Progressive (720P), ABC's selected HDTV format, with 5.1-channel surround sound.

A TV parental guideline will be assigned closer to airdate.