CRISTINA IS FORCED TO CHOOSE HER REPLACEMENT FOR THE FIRST SOLO SURGERY AWARDED TO A RESIDENT, ON ABC'S "GREY'S ANATOMY"

Guest Starring Kevin McKidd ("Rome") as Owen and Melissa George ("Alias," "In Treatment") as Sadie

Guest Starring Academy Award �-nominated Actress Mary McDonnell ("Passion Fish," "Battlestar Gallactica")

"All By Myself" � Cristina is awarded the first solo surgery among the residents, but must give it up and choose her replacement. Meanwhile Mark performs a cutting edge procedure to restore a patient's ability to speak -- and impresses Lexie in the process -- and Callie can't figure out if Sadie is just friendly or flirtatious, on "Grey's Anatomy," THURSDAY, DECEMBER 4 (9:00-10:01 p.m., ET) on the ABC Television Network

"Grey's Anatomy" stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Katherine Heigl as Isobel "Izzie" Stevens, Justin Chambers as Alex Karev, T.R. Knight as George O'Malley, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Eric Dane as Mark Sloan, and Chyler Leigh as Lexie Grey.

Guest cast TBA.

"All By Myself" was written by Peter Nowalk and directed by Arlene Sanford.

"Grey's Anatomy" is broadcast in 720 Progressive (720P), ABC's selected HDTV format, with 5.1-channel surround sound and Spanish audio via SAP. A TV parental guideline will be posted closer to airdate.

This episode of "Grey's Anatomy" will be available on ABC.com the day after airing on the network for users to watch online.