DEREK PERFORMS THE HARDEST SURGERY OF HIS CAREER ON A HOSPITAL CO-WORKER, DESPITE THE CHIEF'S STRONG OBJECTIONS, ON ABC'S "GREY'S ANATOMY"

Directed by Emmy-nominated Chandra Wilson (Dr. Miranda Bailey)

"Give Peace a Chance" � When Isaac, the hospital lab tech, has an inoperable tumor wrapped around his spine, he turns to Dr. Derek Shepherd to do the impossible, and Derek tests the Chief's authority when Richard objects to moving forward with the risky surgery, on "Grey's Anatomy," THURSDAY, OCTOBER 29 (9:00-10:01 p.m., ET) on the ABC Television Network.

"Grey's Anatomy" stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Katherine Heigl as Isobel "Izzie" Stevens, Justin Chambers as Alex Karev, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Eric Dane as Mark Sloan, Chyler Leigh as Lexie Grey, Kevin McKidd as Owen Hunt and Jessica Capshaw as Arizona Robbins.

Guest cast TBA.

"Give Peace a Chance" was written by Peter Nowalk and directed by Chandra Wilson.

"Grey's Anatomy" is broadcast in 720 Progressive (720P), ABC's selected HDTV format, with 5.1-channel surround sound and Spanish subtitles via secondary closed captioning. A TV parental guideline will be posted closer to airdate.

For more information on "Grey's Anatomy," visit ABC.com.